Department of Chemistry

College of Letters & Science
Luo NH, Liao JH, Ouyang L, Wen HL, Zhong YH, Liu JT, et al.. Highly Selective Hydroxylation and Alkoxylation of Silanes: One-Pot Silane Oxidation and Reduction of Aldehydes/Ketones. Organometallics. 2020;39:165-171.
Wu H, Liu BK, Yang K, Winston-McPherson GN, Leisten ED, Vezina CM, et al.. Synthesis and biological evaluation of FICZ analogues as agonists of aryl hydrocarbon receptor. Bioorganic & Medicinal Chemistry Letters. 2020;30.
Blaszczyk SA, Glazier DA, Tang WP. Rhodium-Catalyzed (5+2) and (5+1) Cycloadditions Using 1,4-Enynes as Five-Carbon Building Blocks. Accounts of Chemical Research. 2020;53:231-243.
Klein MA, Liu C, Kuznetsov VI, Feltenberger JB, Tang WP, Denu JM. Mechanism of activation for the sirtuin 6 protein deacylase. Journal of Biological Chemistry. 2020;295:1385-1399.
Yang K, Wu H, Zhang ZR, Leisten ED, Nie XQ, Liu BK, et al.. Development of Selective Histone Deacetylase 6 (HDAC6) Degraders Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. Acs Medicinal Chemistry Letters. 2020;11:575-581.
Liu JT, Ye WJ, Wang SJ, Zheng JR, Tang WP, Li XX. Synthesis of Lactams via Ir-Catalyzed C-H Amidation Involving Ir-Nitrene Intermediates. Journal of Organic Chemistry. 2020;85:4430-4440.
Glazier DA, Liao JZ, Roberts BL, Li XL, Yang K, Stevens CM, et al.. Chemical Synthesis and Biological Application of Modified Oligonucleotides. 2020;31:1213-1233.
Roberts BL, Ma ZX, Gao A, Leisten ED, Yin D, Xu W, et al.. Two-Stage Strategy for Development of Proteolysis Targeting Chimeras and its Application for Estrogen Receptor Degraders. ACS Chemical Biology. 2020;15:1487-1496.
Yang K, Zhao Y, Nie XQ, Wu H, Wang B, Almodovar-Rivera CM, et al.. A Cell-Based Target Engagement Assay for the Identification of Cereblon E3 Ubiquitin Ligase Ligands and Their Application in HDAC6 Degraders. Cell Chemical Biology. 2020;27:866-+.
Wen P, Simmons CJ, Ma ZX, Blaszczyk SA, Balzer PG, Ye WJ, et al.. Synthesis of Glycosyl Chlorides and Bromides by Chelation Assisted Activation of Picolinic Esters under Mild Neutral Conditions. Organic Letters. 2020;22:1495-1498.
Blaszczyk SA, Homan TC, Tang WP. Recent advances in site-selective functionalization of carbohydrates mediated by organocatalysts. Carbohydrate Research. 2019;471:64-77.
Zhao CG, Glazier DA, Yang DS, Yin D, Guzei IA, Aristov MM, et al.. Intermolecular Regio- and Stereoselective Hetero- 5+2 Cycloaddition of Oxidopyrylium Ylides and Cyclic Imines. Angewandte Chemie-International Edition. 2019;58:887-891.
Li JD, Tang WP, Ren DM, Xu JX, Yang ZH. Iridium-catalysed highly selective reduction-elimination of steroidal 4-en-3-ones to 3,5-dienes in water. Green Chemistry. 2019;21:2088-2094.
Wang B, Wu SZ, Liu J, Yang K, Xie HB, Tang WP. Development of selective small molecule MDM2 degraders based on nutlin. European Journal of Medicinal Chemistry. 2019;176:476-491.
Sehgal PD, Bauman TM, Nicholson TM, Vellky JE, Ricke EA, Tang WP, et al.. Tissue-specific quantification and localization of androgen and estrogen receptors in prostate cancer. Human Pathology. 2019;89:99-108.
Blaszczyk SA, Xiao GZ, Wen P, Hao H, Wu J, Wang B, et al.. S-Adamantyl Group Directed Site-Selective Acylation: Applications in Streamlined Assembly of Oligosaccharides. Angewandte Chemie-International Edition. 2019;58:9542-9546.
Winston-McPherson GN, Xie HB, Yang K, Li XX, Shu DX, Tang WP. Discovery of 2,3 '-diindolylmethanes as a novel class of PCSK9 modulators. Bioorganic & Medicinal Chemistry Letters. 2019;29:2345-2348.
Wu H, Yang K, Zhang ZR, Leisten ED, Li ZY, Xie HB, et al.. Development of Multifunctional Histone Deacetylase 6 Degraders with Potent Antimyeloma Activity. Journal of Medicinal Chemistry. 2019;62:7042-7057.
Luo NH, Liao JH, Ouyang L, Wen HL, Liu JT, Tang WP, et al.. Highly pH-Dependent Chemoselective Transfer Hydrogenation of alpha,beta-Unsaturated Aldehydes in Water. Organometallics. 2019;38:3025-3031.
Zhao CG, Ye ZQ, Ma ZX, Wildman SA, Blaszczyk SA, Hu LH, et al.. A general strategy for diversifying complex natural products to polycyclic scaffolds with medium-sized rings. Nature Communications. 2019;10.
Cui YS, Yang K, Tabang DN, Huang JF, Tang WP, Li LJ. Finding the Sweet Spot in ERLIC Mobile Phase for Simultaneous Enrichment of N-Glyco and Phosphopeptides. Journal of the American Society for Mass Spectrometry. 2019;30:2491-2501.
Wu JC, Li XL, Qi XT, Duan XY, Cracraft WL, Guzei IA, et al.. Site-Selective and Stereoselective O-Alkylation of Glycosides by Rh(II)-Catalyzed Carbenoid Insertion. Journal of the American Chemical Society. 2019;141:19902-19910.
Zhu ZP, Wang HY, Simmons C, Tseng PS, Qiu X, Zhang Y, et al.. Iridium-Catalyzed Dynamic Kinetic Stereoselective Allylic Etherification of Achmatowicz Rearrangement Products. Advanced Synthesis & Catalysis. 2018;360:595-599.
Seok SH, Ma ZX, Feltenberger JB, Chen HB, Chen H, Scarlett C, et al.. Trace derivatives of kynurenine potently activate the aryl hydrocarbon receptor (AHR). Journal of Biological Chemistry. 2018;293:1994-2005.
Liu JT, Yang SY, Tang WP, Yang ZH, Xu JX. Iridium-catalyzed efficient reduction of ketones in water with formic acid as a hydride donor at low catalyst loading. Green Chemistry. 2018;20:2118-2124.
Zhu ZP, Glazier DA, Yang DS, Tang WP. Catalytic Asymmetric Synthesis of All Possible Stereoisomers of 2,3,4,6-Tetradeoxy-4-Aminohexopyranosides. Advanced Synthesis & Catalysis. 2018;360:2211-2215.
Yang SY, Tang WP, Yang ZH, Xu JX. Iridium-Catalyzed Highly Efficient and Site-Selective Deoxygenation of Alcohols. Acs Catalysis. 2018;8:9320-9326.
Glazier DA, Schroeder JM, Liu JT, Tang WP. Organocatalyst-Mediated Dynamic Kinetic Enantioselective Acylation of 2-Chromanols. Advanced Synthesis & Catalysis. 2018;360:4646-4649.
Wang HY, Simmons CJ, Zhang Y, Smits AM, Balzer PG, Wang SJ, et al.. Chiral Catalyst-Directed Dynamic Kinetic Diastereoselective Acylation of Anomeric Hydroxyl Groups and a Controlled Reduction of the Glycosyl Ester Products. Organic Letters. 2017;19:508-511.
Liu JT, Simmons CJ, Xie HB, Yang F, Zhao XL, Tang Y, et al.. Synthesis of Highly Substituted Benzofuran-containing Natural Products via Rh-catalyzed Carbonylative Benzannulation. Advanced Synthesis & Catalysis. 2017;359:693-697.
Xiao GZ, Cintron-Rosado GA, Glazier DA, Xi BM, Liu C, Liu P, et al.. Catalytic Site-Selective Acylation of Carbohydrates Directed by Cation-n Interaction. Journal of the American Chemical Society. 2017;139:4346-4349.
Song WZ, Wang SJ, Tang WP. De Novo Synthesis of Mono- and Oligosaccharides via Dihydropyran Intermediates. Chemistry-an Asian Journal. 2017;12:1027-1042.
Yang ZH, Zhu ZP, Luo RS, Qiu X, Liu JT, Yang JK, et al.. Iridium-catalyzed highly efficient chemoselective reduction of aldehydes in water using formic acid as the hydrogen source. Green Chemistry. 2017;19:3296-3301.
Song WZ, Blaszczyk SA, Liu JT, Wang SJ, Tang WP. Transition metal mediated carbonylative benzannulations. Organic & Biomolecular Chemistry. 2017;15:7490-7504.
Yang ZH, Luo RS, Zhu ZP, Yang XR, Tang WP. Harnessing the Reactivity of Iridium Hydrides by Air: Iridium-Catalyzed Oxidation of Aldehydes to Acids in Water. Organometallics. 2017;36:4095-4098.
Wang HY, Simmons CJ, Blaszczyk SA, Balzer PG, Luo RS, Duan XY, et al.. Isoquinoline-1-Carboxylate as a Traceless Leaving Group for Chelation-Assisted Glycosylation under Mild and Neutral Reaction Conditions. Angewandte Chemie-International Edition. 2017;56:15698-15702.
Jaskula-Sztul R, Chen GJ, Dammalapati A, Harrison A, Tang WP, Gong S, et al.. AB3-loaded and tumor-targeted unimolecular micelles for medullary thyroid cancer treatment. Journal of Materials Chemistry B. 2017;5:151-159.
Chen GJ, Jaskula-Sztul R, Esquibel CR, Lou I, Zheng QF, Dammalapati A, et al.. Neuroendocrine Tumor-Targeted Upconversion Nanoparticle-Based Micelles for Simultaneous NIR-Controlled Combination Chemotherapy and Photodynamic Therapy, and Fluorescence Imaging. Advanced Functional Materials. 2017;27:1604671.
Liu JT, Do TJ, Simmons CJ, Lynch JC, Gu W, Ma ZX, et al.. Total synthesis of diptoindonesin G and its analogues as selective modulators of estrogen receptors. Organic & Biomolecular Chemistry. 2016;14:8927-8930.
Liu RS, Wang JH, Tang WP, Fang H. Design and synthesis of a new generation of substituted purine hydroxamate analogs as histone deacetylase inhibitors. Bioorganic & Medicinal Chemistry. 2016;24:1446-1454.
Song WZ, Li XX, Yang K, Zhao XL, Glazier DA, Xi BM, et al.. Synthesis of Carbazoles and Carbazole-Containing Heterocycles via Rhodium-Catalyzed Tandem Carbonylative Benzannulations. Journal of Organic Chemistry. 2016;81:2930-2942.
Li XX, Song WZ, Ke XN, Xu XF, Liu P, Houk KN, et al.. Rhodium-Catalyzed Intramolecular 5+2 Cycloaddition of Inverted 3-Acyloxy-1,4-enyne and Alkyne: Experimental and Theoretical Studies. Chemistry-A European Journal. 2016;22:7079-7083.
Song WZ, Lynch JC, Shu XZ, Tang WP. Rhodium-Catalyzed 5+2 Cycloaddition of 3-Acyloxy-1,4-enyne with Alkene or Allene. Advanced Synthesis & Catalysis. 2016;358:2007-2011.
Li XX, Xie HB, Fu XN, Liu JT, Wang HY, Xi BM, et al.. Rhodium(I)-Catalyzed Benzannulation of Heteroaryl Propargylic Esters: Synthesis of Indoles and Related Heterocycles. Chemistry-A European Journal. 2016;22:10410-10414.
Hideshima T, Qi J, Paranal RM, Tang WP, Greenberg E, West N, et al.. Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma. Proceedings of the National Academy of Sciences of the United States of America. 2016;113:13162-13167.
Shu XZ, Schienebeck CM, Li XX, Zhou X, Song WZ, Chen LQ, et al.. Rhodium-Catalyzed Stereoselective Intramolecular 5+2 Cycloaddition of 3-Acyloxy 1,4-Enyne and Alkene. Organic Letters. 2015;17:5128-5131.
Li XX, Li H, Song WZ, Tseng PS, Liu LY, Guzei IA, et al.. Divergent Reactivity of Rhodium(I) Carbenes Derived from Indole Annulations. Angewandte Chemie-International Edition. 2015;53:12905-12908.
Song WZ, Zhao Y, Lynch JC, Kim H, Tang WP. Divergent de novo synthesis of all eight stereoisomers of 2,3,6-trideoxyhexopyranosides and their oligomers. Chemical Communications. 2015;51:17475-17478.
Jaskula-Sztul R, Eide J, Tesfazghi S, Dammalapati A, Harrison AD, Yu XM, et al.. Tumor-Suppressor Role of Notch3 in Medullary Thyroid Carcinoma Revealed by Genetic and Pharmacological Induction. Molecular Cancer Therapeutics. 2015;14:499-512.
Schienebeck CM, Song WZ, Smits AM, Tang WP. Rhodium-Catalyzed Intermolecular 5+1 and 5+2 Cycloadditions Using 1,4-Enynes with an Electron-Donating Ester on the 3-Position. Synthesis-Stuttgart. 2015;47:1076-1084.
Ke XN, Schienebeck CM, Zhou CC, Xu XF, Tang WP. Mechanism and reactivity of rhodium-catalyzed intermolecular 5+1 cycloaddition of 3-acyloxy-1,4-enyne (ACE) and CO: A computational study. Chinese Chemical Letters. 2015;26:730-734.
Wang HY, Yang K, Bennett SR, Guo SR, Tang WP. Iridium-Catalyzed Dynamic Kinetic Isomerization: Expedient Synthesis of Carbohydrates from Achmatowicz Rearrangement Products. Angewandte Chemie-International Edition. 2015;54:8756-8759.
Wang L, Hou XB, Fu HS, Pan XL, Xu WF, Tang WP, et al.. Design, synthesis and preliminary bioactivity evaluations of substituted quinoline hydroxamic acid derivatives as novel histone deacetylase (HDAC) inhibitors. Bioorganic & Medicinal Chemistry. 2015;23:4364-4374.
Song WZ, Xi BM, Yang K, Tang WP. Synthesis of substituted tropones by sequential Rh-catalyzed 5+2 cycloaddition and elimination. Tetrahedron. 2015;71:5979-5984.
Wang HY, Yang K, Yin D, Liu C, Glazier DA, Tang WP. Chiral Catalyst-Directed Dynamic Kinetic Diastereoselective Acylation of Lactols for De Novo Synthesis of Carbohydrate. Organic Letters. 2015;17:5272-5275.
Li H, Li XX, Wang HY, Winston-McPherson GN, Geng HMJ, Guzei IA, et al.. Copper-catalyzed tandem annulation/arylation for the synthesis of diindolylmethanes from propargylic alcohols. Chemical Communications. 2014;50:12293-12296.
Wang JH, Sun FE, Han LQ, Hou XB, Pan XL, Liu RS, et al.. Design, synthesis, and preliminary bioactivity studies of substituted purine hydroxamic acid derivatives as novel histone deacetylase (HDAC) inhibitors. Medchemcomm. 2014;5:1887-1891.
Wang HY, Zhang W, Schienebeck CM, Bennett SR, Tang WP. Intermolecular bromoesterification of conjugated enynes: an efficient synthesis of bromoallenes. Organic Chemistry Frontiers. 2014;1:386-390.
Han LQ, Wang L, Hou XB, Fu HS, Song WG, Tang WP, et al.. Design, synthesis and preliminary bioactivity studies of 1,2-dihydrobenzo d isothiazol-3-one-1,1-dioxide hydroxamic acid derivatives as novel histone deacetylase inhibitors. Bioorganic & Medicinal Chemistry. 2014;22:1529-1538.
Schienebeck CM, Li XX, Shu XZ, Tang WP. 3-Acyloxy-1,4-enyne: A new five-carbon synthon for rhodium-catalyzed 5+2 cycloadditions. Pure and Applied Chemistry. 2014;86:409-417.
Zheng SQ, Schienebeck CM, Zhang W, Wang HY, Tang WP. Cinchona Alkaloids as Organocatalysts in Enantioselective Halofunctionalization of Alkenes and Alkynes. Asian Journal of Organic Chemistry. 2014;3:366-376.
Winston-McPherson GN, Shu DX, Tang WP. Synthesis and biological evaluation of 2,3 '-diindolylmethanes as agonists of aryl hydrocarbon receptor. Bioorganic & Medicinal Chemistry Letters. 2014;24:4023-4025.
Guan P, Wang L, Hou XB, Wan YC, Xu WF, Tang WP, et al.. Improved antiproliferative activity of 1,3,4-thiadiazole-containing histone deacetylase (HDAC) inhibitors by introduction of the heteroaromatic surface recognition motif. Bioorganic & Medicinal Chemistry. 2014;22:5766-5775.
Liu N, Song WZ, Schienebeck CM, Zhang M, Tang WP. Synthesis of naturally occurring tropones and tropolones. Tetrahedron. 2014;70:9281-9305.
Zhang W, Liu N, Schienebeck CM, Zhou X, , Guzei IA, et al.. Enantioselective intermolecular bromoesterification of allylic sulfonamides. Chemical Science. 2013;4:2652-2656.
Shu XZ, Schienebeck CM, Song WZ, Guzei IA, Tang WP. Transfer of Chirality in the Rhodium-Catalyzed Intramolecular 5+2 Cycloaddition of 3-Acyloxy-1,4-enynes (ACEs) and Alkynes: Synthesis of Enantioenriched Bicyclo 5.3.0 decatrienes. Angewandte Chemie-International Edition. 2013;52:13601-13605.
Liu RH, Winston-McPherson GN, Yang ZY, Zhou X, Song WZ, Guzei IA, et al.. Generation of Rhodium(I) Carbenes from Ynamides and Their Reactions with Alkynes and Alkenes. Journal of the American Chemical Society. 2013;135:8201-8204.
Liu N, Wang HY, Zhang W, Jia ZH, Guzei IA, Xu HD, et al.. Stereoselective Halocyclization of Alkenes With N-Acyl Hemiaminal Nucleophiles. Chirality. 2013;25:805-809.
Fass DM, Reis SA, Ghosh B, Hennig KM, Joseph NF, Zhao WN, et al.. Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity. Neuropharmacology. 2013;64:81-96.
Schienebeck CM, Robichaux PJ, Li XX, Chen LQ, Tang WP. Effect of ester on rhodium-catalyzed intermolecular 5+2 cycloaddition of 3-acyloxy-1,4-enynes and alkynes. Chemical Communications. 2013;49:2616-2618.
Shu DX, Song WZ, Li XX, Tang WP. Rhodium- and Platinum-Catalyzed 4+3 Cycloaddition with Concomitant Indole Annulation: Synthesis of Cyclohepta b indoles. Angewandte Chemie-International Edition. 2013;52:3237-3240.
Liu RH, Zhang M, Winston-McPherson G, Tang WP. Ring expansion of alkynyl cyclopropanes to highly substituted cyclobutenes via a N-sulfonyl-1,2,3-triazole intermediate. Chemical Communications. 2013;49:4376-4378.
Xu HD, Zhang RW, Li XX, Huang SY, Tang WP, Hu WH. Rhodium-Catalyzed Chemo- and Regioselective Cross-Dimerization of Two Terminal Alkynes. Organic Letters. 2013;15:840-843.
Zheng J, Xu CM, Guo J, Wei Y, Ge HJ, Li XC, et al.. Effective Noninvasive Zygosity Determination by Maternal Plasma Target Region Sequencing. Plos One. 2013;8.
Xu XF, Liu P, Shu XZ, Tang WP, Houk KN. Rh-Catalyzed (5+2) Cycloadditions of 3-Acyloxy-1,4-enynes and Alkynes: Computational Study of Mechanism, Reactivity, and Regioselectivity. Journal of the American Chemical Society. 2013;135:9271-9274.
Shu DX, Winston-McPherson GN, Song WZ, Tang WP. Platinum-Catalyzed Tandem Indole Annulation/Arylation for the Synthesis of Diindolylmethanes and Indolo 3,2-b carbazoles. Organic Letters. 2013;15:4162-4165.
Zhang M, Liu N, Tang WP. Stereoselective Total Synthesis of Hainanolidol and Harringtonolide via Oxidopyrylium-Based 5+2 Cycloaddition. Journal of the American Chemical Society. 2013;135:12434-12438.
Li XX, Song WZ, Tang WP. Rhodium-Catalyzed Tandem Annulation and (5+1) Cycloaddition: 3-Hydroxy-1,4-enyne as the 5-Carbon Component. Journal of the American Chemical Society. 2013;135:16797-16800.
Jarecki BW, Zheng SQ, Zhang LL, Li XX, Zhou X, Cui Q, et al.. Tethered Spectroscopic Probes Estimate Dynamic Distances with Subnanometer Resolution in Voltage-Dependent Potassium Channels. Biophysical Journal. 2013;105:2724-2732.
Shu DX, Li XX, Zhang M, Robichaux PJ, Guzei IA, Tang WP. Rhodium-Catalyzed Carbonylation of Cyclopropyl Substituted Propargyl Esters: A Tandem 1,3-Acyloxy Migration 5+1 Cycloaddition. Journal of Organic Chemistry. 2012;77:6463-6472.
Huang SY, Li XX, Lin CL, Guzei IA, Tang WP. Rhodium-catalyzed 1,3-acyloxy migration and subsequent intramolecular 4+2 cycloaddition of vinylallene and unactivated alkyne. Chemical Communications. 2012;48:2204-2206.
Liu RH, Zhang M, Wyche TP, Winston-McPherson GN, Bugni TS, Tang WP. Stereoselective Preparation of Cyclobutanes with Four Different Substituents: Total Synthesis and Structural Revision of Pipercyclobutanamide A and Piperchabamide G. Angewandte Chemie-International Edition. 2012;51:7503-7506.
Shu XZ, Shu DX, Schienebeck CM, Tang WP. Rhodium-catalyzed acyloxy migration of propargylic esters in cycloadditions, inspiration from the recent "gold rush". Chemical Society Reviews. 2012;41:7698-7711.
Li XX, Huang SY, Schienebeck CM, Shu DX, Tang WP. Rhodium-Catalyzed Carbonylation of 3-Acyloxy-1,4-enynes for the Synthesis of Cyclopentenones. Organic Letters. 2012;14:1584-1587.
Shu XZ, Li XX, Shu DX, Huang SY, Schienebeck CM, Zhou X, et al.. Rhodium-Catalyzed Intra- and Intermolecular 5+2 Cycloaddition of 3-Acyloxy-1,4-enyne and Alkyne with Concomitant 1,2-Acyloxy Migration. Journal of the American Chemical Society. 2012;134:5211-5221.
Zhang W, Liu N, Schienebeck CM, Decloux K, Zheng SQ, Werness JB, et al.. Catalytic Enantioselective Halolactonization of Enynes and Alkenes. Chemistry-A European Journal. 2012;18:7296-7305.
Zhang M, Tang WP. Synthesis of Functionalized Cyclohexenone Core of Welwitindolinones via Rhodium-Catalyzed 5+1 Cycloaddition. Organic Letters. 2012;14:3756-3759.
Werness JB, Tang WP. Synthesis of bromoallenyl pyrrolidines via 1,4-addition to 1,3-enynes. Science China-Chemistry. 2011;54:56-60.
Li XX, Zhang M, Shu DX, Robichaux PJ, Huang SY, Tang WP. Rhodium-Catalyzed Ring Expansion of Cyclopropanes to Seven-membered Rings by 1,5 C-C Bond Migration. Angewandte Chemie-International Edition. 2011;50:10421-10424.
Shu XZ, Huang SY, Shu DX, Guzei IA, Tang WP. Interception of a Rautenstrauch Intermediate by Alkynes for 5+2 Cycloaddition: Rhodium-Catalyzed Cycloisomerization of 3-Acyloxy-4-ene-1,9-diynes to Bicyclo 5.3.0 decatrienes. Angewandte Chemie-International Edition. 2011;50:8153-8156.
Shu DX, Li XX, Zhang M, Robichaux PJ, Tang WP. Synthesis of Highly Functionalized Cyclohexenone Rings: Rhodium-Catalyzed 1,3-Acyloxy Migration and Subsequent 5+1 Cycloaddition. Angewandte Chemie-International Edition. 2011;50:1346-1349.
Tang WP, Luo TP, Greenberg EF, Bradner JE, Schreiber SL. Discovery of histone deacetylase 8 selective inhibitors. Bioorganic & Medicinal Chemistry Letters. 2011;21:2601-2605.
Liu N, Werness JB, Guzei IA, Tang WP. Intramolecular 1,4-addition of nitrogen nucleophile and bromine electrophile to conjugated 1,3-enyne. Tetrahedron. 2011;67:4385-4390.
Werness JB, Tang WP. Stereoselective Total Synthesis of (-)-Kumausallene. Organic Letters. 2011;13:3664-3666.
Liu N, Schienebeck CM, Collier MD, Tang WP. Effect of halogenation reagents on halocyclization and Overman rearrangement of allylic trichloroacetimidates. Tetrahedron Letters. 2011;52:6217-6219.
Zhang W, Zheng SQ, Liu N, Werness JB, Guzei IA, Tang WP. Enantioselective Bromolactonization of Conjugated (Z)-Enynes. Journal of the American Chemical Society. 2010;132:3664-+.
Fu QS, Boonchayaanant B, Tang WP, Trost BM, Criddle CS. Simple menaquinones reduce carbon tetrachloride and iron (III). Biodegradation. 2009;20:109-116.
Zhang W, Xu HD, Xu H, Tang WP. DABCO-Catalyzed 1,4-Bromolactonization of Conjugated Enynes: Highly Stereoselective Formation of a Stereogenic Center and an Axially Chiral Allene. Journal of the American Chemical Society. 2009;131:3832-+.
Borowiak M, Maehr R, Chen SB, Chen AE, Tang WP, Fox JL, et al.. Small Molecules Efficiently Direct Endodermal Differentiation of Mouse and Human Embryonic Stem Cells. Cell Stem Cell. 2009;4:348-358.
Zhang W, Werness JB, Tang WP. Intramolecular hydroamination of conjugated enynes. Tetrahedron. 2009;65:3090-3095.
Patel V, Mazitschek R, Coleman B, Nguyen C, Urgaonkar S, Cortese J, et al.. Identification and Characterization of Small Molecule Inhibitors of a Class I Histone Deacetylase from Plasmodium falciparum. Journal of Medicinal Chemistry. 2009;52:2185-2187.
Um JM, Xu HD, Houk KN, Tang WP. Thermodynamic Control of the Electrocyclic Ring Opening of Cyclobutenes: C=X Substituents at C-3 Mask the Kinetic Torquoselectivity. Journal of the American Chemical Society. 2009;131:6664-+.
Xu HD, Zhang W, Shu DX, Werness JB, Tang WP. Synthesis of Cyclobutenes by Highly Selective Transition-Metal-Catalyzed Ring Expansion of Cyclopropanes. Angewandte Chemie-International Edition. 2008;47:8933-8936.
Zhang W, Werness JB, Tang WP. Base-catalyzed intramolecular hydroamination of conjugated enynes. Organic Letters. 2008;10:2023-2026.
Vegas AJ, Bradner JE, Tang WP, McPherson OM, Greenberg EF, Koehler AN, et al.. Fluorous-based small-molecule microarrays for the discovery of histone deacetylase inhibitors. Angewandte Chemie-International Edition. 2007;46:7960-7964.
Trost BM, Tang WP, Toste FD. Divergent enantioselective synthesis of (-)-galanthamine and (-)-morphine. Journal of the American Chemical Society. 2005;127:14785-14803.
Trost BM, Tang WP. Migratory hydroamination: A facile enantioselective synthesis of benzomorphans. Journal of the American Chemical Society. 2003;125:8744-8745.
Trost BM, Tang WP. An efficient enantioselective synthesis of (-)-galanthamine. Angewandte Chemie-International Edition. 2002;41:2795-+.
Trost BM, Tang WP. Enantioselective synthesis of (-)-codeine and (-)-morphine. Journal of the American Chemical Society. 2002;124:14542-14543.
Trost BM, Tang WP. An enantioselective strategy to macrocyclic bisindolylmaleimides. An efficient formal synthesis of LY 333531. Organic Letters. 2001;3:3409-3411.
Trost BM, Tang WP, Schulte JL. Asymmetric synthesis of quaternary centers. Total synthesis of (-)-malyngolide. Organic Letters. 2000;2:4013-4015.
Sun LH, Li P, Amankulor N, Tang WP, Landry DW, Zhao K. N-alkoxy analogues of 3,4,5-trihydroxypiperidine. Journal of Organic Chemistry. 1998;63:6472-6475.