Department of Chemistry

College of Letters & Science
Cui YS, Tabang DN, Zhang ZS, Ma M, Alpert AJ, Li LJ. Counterion Optimization Dramatically Improves Selectivity for Phosphopeptides and Glycopeptides in Electrostatic Repulsion-Hydrophilic Interaction Chromatography. Analytical Chemistry. 2021;93:7908-7916.
Li ZH, Tremmel DM, Ma FF, Yu QY, Ma M, Delafield DG, et al. Proteome-wide and matrisome-specific alterations during human pancreas development and maturation. Nature Communications. 2021;12.
DeLaney K, Hu MZ, Hellenbrand T, Dickinson PS, Nusbaum MP, Li LJ. Mass Spectrometry Quantification, Localization, and Discovery of Feeding-Related Neuropeptides in Cancer borealis. ACS Chemical Neuroscience. 2021;12:782-798.
Dieterich IA, Cui YS, Braun MM, Lawton AJ, Robinson NH, Peotter JL, et al. Acetyl-CoA flux from the cytosol to the ER regulates engagement and quality of the secretory pathway. Scientific Reports. 2021;11.
Gao J, Lin PH, Nick ST, Huang JF, Tykesson E, Ellervik U, et al. Chemoenzymatic Synthesis of Glycopeptides Bearing Galactose-Xylose Disaccharide from the Proteoglycan Linkage Region. 2021;23:1738-1741.
Thomas S, Dunn CD, Campbell LJ, Strand DW, Vezina CM, Bjorling DE, et al. A multi-omic investigation of male lower urinary tract symptoms: Potential role for JC virus. Plos One. 2021;16.
Vu NQ, Buchberger AR, Johnson J, Li LJ. Complementary neuropeptide detection in crustacean brain by mass spectrometry imaging using formalin and alternative aqueous tissue washes. Analytical and Bioanalytical Chemistry. 2021;.
Dias LD, Dobson HE, Bakke BK, Kujoth GC, Huang JF, Kohn EM, et al. Structural basis of Blastomyces Endoglucanase-2 adjuvancy in anti-fungal and -viral immunity. Plos Pathogens. 2021;17.
Vu NQ, DeLaney K, Li LJ. Neuropeptidomics: Improvements in Mass Spectrometry Imaging Analysis and Recent Advancements. Current Protein & Peptide Science. 2021;22:158-169.
Zhang H, Xu M, Shi XD, Liu Y, Li ZH, Jagodinsky JC, et al. Quantification and molecular imaging of fatty acid isomers from complex biological samples by mass spectrometry. Chemical Science. 2021;.
Delafield DG, Li LJ. Recent Advances in Analytical Approaches for Glycan and Glycopeptide Quantitation. Molecular & Cellular Proteomics. 2021;20.
Hu MZ, Helfenbein K, Buchberger AR, DeLaney K, Liu Y, Li LJ. Exploring the Sexual Dimorphism of Crustacean Neuropeptide Expression Using Callinectes sapidus as a Model Organism. Journal of Proteome Research. 2021;20:2739-2750.
Kishimoto AO, Kishimoto Y, Shi XD, Hutchinson EB, Zhang H, Shi YT, et al. High-resolution magnetic resonance and mass spectrometry imaging of the human larynx. Journal of Anatomy. 2021;.
Sauer CS, Li LJ. Mass Spectrometric Profiling of Neuropeptides in Response to Copper Toxicity via Isobaric Tagging. Chemical Research in Toxicology. 2021;34:1329-1336.
Huang JF, Wang DQ, Shipman RD, Zhu ZX, Liu Y, Li LJ. Simultaneous enrichment and separation of neutral and sialyl glycopeptides of SARS-CoV-2 spike protein enabled by dual-functionalized Ti-IMAC material. Analytical and Bioanalytical Chemistry. 2021;.
DeLaney K, Hu MZ, Wu WX, Nusbaum MP, Li LJ. Mass spectrometry profiling and quantitation of changes in circulating hormones secreted over time in Cancer borealis hemolymph due to feeding behavior. Analytical and Bioanalytical Chemistry. 2021;.
Huang JF, Liu XY, Wang DQ, Cui YS, Shi XD, Dong J, et al. Dual-Functional Ti(IV)-IMAC Material Enables Simultaneous Enrichment and Separation of Diverse Glycopeptides and Phosphopeptides. Analytical Chemistry. 2021;93:8568-8576.
Tabang DN, Cui YS, Tremmel DM, Ford M, Li ZH, Sackett SD, et al. Analysis of pancreatic extracellular matrix protein post-translational modifications via electrostatic repulsion-hydrophilic interaction chromatography coupled with mass spectrometry. Molecular Omics. 2021;.
Li MY, Gu TJ, Lin XR, Li LJ. DiLeuPMP: A Multiplexed Isobaric Labeling Method for Quantitative Analysis of O-Glycans. Analytical Chemistry. 2021;93:9845-9852.
Gant KL, Jambor AN, Li ZH, Rentchler EC, Weisman P, Li LJ, et al. Evaluation of Collagen Alterations in Early Precursor Lesions of High Grade Serous Ovarian Cancer by Second Harmonic Generation Microscopy and Mass Spectrometry. Cancers. 2021;13.
Hou LK, Li Y, Wu QH, Li MY, Older EA, Tang XY, et al. Discovery of anti-infective adipostatins through bioactivity-guided isolation and heterologous expression of a type III polyketide synthase. Bioorganic Chemistry. 2021;112.
Chen ZW, Yu QY, Yu Q, Johnson J, Shipman R, Zhong XF, et al. In-depth Site-specific Analysis of N-glycoproteome in Human Cerebrospinal Fluid and Glycosylation Landscape Changes in Alzheimer's Disease. Molecular & Cellular Proteomics. 2021;20.
Tabang DN, Ford M, Li LJ. Recent Advances in Mass Spectrometry-Based Glycomic and Glycoproteomic Studies of Pancreatic Diseases. Frontiers in Chemistry. 2021;9.
Miles HN, Delafield DG, Li LJ. Recent developments and applications of quantitative proteomics strategies for high-throughput biomolecular analyses in cancer research. Rsc Chemical Biology. 2021;2:1050-1072.
Sauer CS, Phetsanthad A, Riusech OL, Li LJ. Developing mass spectrometry for the quantitative analysis of neuropeptides. Expert Review of Proteomics. 2021;18:607-621.
Liu FB, Ma M, Gao A, Ma FF, Ma G, Liu P, et al. PKM2-TMEM33 axis regulates lipid homeostasis in cancer cells by controlling SCAP stability. EMBO Journal. 2021;:e108065.
Atkinson LE, Liu Y, McKay F, Vandewyer E, Viau C, Irvine A, et al. Ascaris suum Informs Extrasynaptic Volume Transmission in Nematodes. ACS Chemical Neuroscience. 2021;12:3176-3188.
Wang JX, Drelich AJ, Hopkins CM, Mecozzi S, Li LJ, Kwon G, et al. Gold nanoparticles in virus detection: Recent advances and potential considerations for SARS-CoV-2 testing development. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology. 2021;:e1754.
Phetsanthad A, Vu NQ, Yu Q, Buchberger AR, Chen ZW, Keller C, et al. Recent advances in mass spectrometry analysis of neuropeptides. Mass Spectrometry Reviews. 2021;:e21734.
Wei PL, Keller C, Li LJ. Neuropeptides in gut-brain axis and their influence on host immunity and stress. Computational and Structural Biotechnology Journal. 2020;18:843-851.
DeLaney K, Li LJ. Neuropeptidomic Profiling and Localization in the Crustacean Cardiac Ganglion Using Mass Spectrometry Imaging with Multiple Platforms. 2020;31:2469-2478.
Lu GY, Xu XW, Li GY, Sun HY, Wang N, Zhu YX, et al. Subresidue-Resolution Footprinting of Ligand-Protein Interactions by Carbene Chemistry and Ion Mobility-Mass Spectrometry. Analytical Chemistry. 2020;92:947-956.
Li GY, Delafield DG, Li LJ. Improved structural elucidation of peptide isomers and their receptors using advanced ion mobility-mass spectrometry. Trac-Trends in Analytical Chemistry. 2020;124.
Thomas S, Hao L, DeLaney K, McLean D, Steinke L, Marker PC, et al. Spatiotemporal Proteomics Reveals the Molecular Consequences of Hormone Treatment in a Mouse Model of Lower Urinary Tract Dysfunction. Journal of Proteome Research. 2020;19:1375-1382.
Buchberger AR, Sauer CS, Vu NQ, DeLaney K, Li LJ. Temporal Study of the Perturbation of Crustacean Neuropeptides Due to Severe Hypoxia Using 4-Plex Reductive Dimethylation. Journal of Proteome Research. 2020;19:1548-1555.
Buchberger AR, Vu NQ, Johnson J, DeLaney K, Li LJ. A Simple and Effective Sample Preparation Strategy for MALDI-MS Imaging of Neuropeptide Changes in the Crustacean Brain Due to Hypoxia and Hypercapnia Stress. 2020;31:1058-1065.
Frost DC, Feng Y, Li LJ. 21-plex DiLeu Isobaric Tags for High-Throughput Quantitative Proteomics. Analytical Chemistry. 2020;92:8228-8234.
DeLaney K, Cao WF, Ma YD, Ma MM, Zhang YZ, Li LJ. PRESnovo: Prescreening Prior to de novo Sequencing to Improve Accuracy and Sensitivity of Neuropeptide Identification. 2020;31:1358-1371.
Yu QY, Zhong XF, Chen BM, Feng Y, Ma M, Diamond CA, et al. Isobaric Labeling Strategy Utilizing 4-Plex N,N-Dimethyl Leucine (DiLeu) Tags Reveals Proteomic Changes Induced by Chemotherapy in Cerebrospinal Fluid of Children with B-Cell Acute Lymphoblastic Leukemia. Journal of Proteome Research. 2020;19:2606-2616.
Zhu JH, Huang JF, Zhang J, Chen ZW, Lin Y, Grigorean G, et al. Glycopeptide Biomarkers in Serum Haptoglobin for Hepatocellular Carcinoma Detection in Patients with Nonalcoholic Steatohepatitis. Journal of Proteome Research. 2020;19:3452-3466.
Zhong XF, Lietz CB, Shi XD, Buchberger AR, Frost DC, Li LJ. Highly multiplexed quantitative proteomic and phosphoproteomic in vascular smooth muscle cell dedifferentiation. Analytica Chimica Acta. 2020;1127:163-173.
Zhong XF, Frost DC, Yu QY, Li MY, Gu TJ, Li LJ. Mass Defect-Based DiLeu Tagging for Multiplexed Data-Independent Acquisition. Analytical Chemistry. 2020;92:11119-11126.
Keller C, Wei PL, Wancewicz B, Cross TWL, Rey FE, Li LJ. Extraction optimization for combined metabolomics, peptidomics, and proteomics analysis of gut microbiota samples. Journal of Mass Spectrometry. 2020;.
Wei PL, Hao L, Thomas S, Buchberger AR, Steinke L, Marker PC, et al. Urinary Amine Metabolomics Characterization with Custom 12-Plex Isobaric DiLeu Labeling. 2020;31:1854-1860.
Buchberger AR, DeLaney K, Liu Y, Vu NQ, Helfenbein K, Li LJ. Mass Spectrometric Profiling of Neuropeptides in Callinectes sapidus during Hypoxia Stress. ACS Chemical Neuroscience. 2020;11:3097-3106.
DeLaney K, Phetsanthad A, Li LJ. Advances in High-Resolution Maldi Mass Spectrometry for Neurobiology. Mass Spectrometry Reviews. 2020;.
Zhang H, Shi XD, Vu NQ, Li GY, Li ZH, Shi YT, et al. On-Tissue Derivatization with Girard's Reagent P Enhances N-Glycan Signals for Formalin-Fixed Paraffin-Embedded Tissue Sections in MALDI Mass Spectrometry Imaging. Analytical Chemistry. 2020;92:13361-13368.
Liu R, Wei PL, Keller C, Orefice NS, Shi YT, Li ZH, et al. Integrated Label-Free and 10-Plex DiLeu Isobaric Tag Quantitative Methods for Profiling Changes in the Mouse Hypothalamic Neuropeptidome and Proteome: Assessment of the Impact of the Gut Microbiome. Analytical Chemistry. 2020;92:14021-14030.
DeLaneya K, Li LJ. Capillary electrophoresis coupled to MALDI mass spectrometry imaging with large volume sample stacking injection for improved coverage of C. borealis neuropeptidome. Analyst. 2020;145:61-69.
Lv YN, Fu J, Jia QQ, Dong HT, Han SL, Li LJ, et al. Liquid Chromatography Tandem Mass Spectrometry Based Label-Free Quantification Method for Assessment of Allergen-Induced Anaphylactoid Reactions. Journal of the American Society for Mass Spectrometry. 2020;31:856-863.
Johnson J, Sharick JT, Skala MC, Li LJ. Sample preparation strategies for high-throughput mass spectrometry imaging of primary tumor organoids. Journal of Mass Spectrometry. 2019;.
Cui YS, Yang K, Tabang DN, Huang JF, Tang WP, Li LJ. Finding the Sweet Spot in ERLIC Mobile Phase for Simultaneous Enrichment of N-Glyco and Phosphopeptides. Journal of the American Society for Mass Spectrometry. 2019;30:2491-2501.
Yan X, Li LJ, Jia CX. Discovery of Missing Methylation Sites on Endogenous Peptides of Human Cell Lines. Journal of the American Society for Mass Spectrometry. 2019;30:2537-2547.
Zhong XF, Wang JX, Carlsson C, Okonkwo O, Zetterberg H, Li LJ. A Strategy for Discovery and Verification of Candidate Biomarkers in Cerebrospinal Fluid of Preclinical Alzheimer's Disease. Frontiers in Molecular Neuroscience. 2019;11.
Zhu JH, Chen ZW, Zhang J, An MR, Wu J, Yu Q, et al. Differential Quantitative Determination of Site-Specific Intact N-Glycopeptides in Serum Haptoglobin between Hepatocellular Carcinoma and Cirrhosis Using LC-EThcD-MS/MS. Journal of Proteome Research. 2019;18:359-371.
Li GY, Cao QJW, Liu Y, DeLaney K, Tian ZC, Moskovets E, et al. Characterizing and alleviating ion suppression effects in atmospheric pressure matrix-assisted laser desorption/ionization. Rapid Communications in Mass Spectrometry. 2019;33:327-335.
DeLaney K, Sauer CS, Vu NQ, Li LJ. Recent Advances and New Perspectives in Capillary Electrophoresis-Mass Spectrometry for Single Cell "Omics". Molecules. 2019;24.
Zhong XF, Yu QY, Ma FF, Frost DC, Lu L, Chen ZW, et al. HOTMAQ: A Multiplexed Absolute Quantification Method for Targeted Proteomics. Analytical Chemistry. 2019;91:2112-2119.
Feng Y, Chen BM, Yu QY, Li LJ. Identification of Double Bond Position Isomers in Unsaturated Lipids by m-CPBA Epoxidation and Mass Spectrometry Fragmentation. Analytical Chemistry. 2019;91:1791-1795.
Feng Y, Chen BM, Yu QY, Zhong XF, Frost DC, Ikonomidou C, et al. Isobaric Multiplex Labeling Reagents for Carbonyl-Containing Compound (SUGAR) Tags: A Probe for Quantitative Glycomic Analysis. Analytical Chemistry. 2019;91:3141-3146.
Cao QJW, Wang YJ, Chen BM, Ma FF, Hao L, Li GY, et al. Visualization and Identification of Neurotransmitters in Crustacean Brain via Multifaceted Mass Spectrometric Approaches. ACS Chemical Neuroscience. 2019;10:1222-1229.
Shi YT, Johnson J, Wang BW, Chen BM, Fisher GL, Urabe G, et al. Mass Spectrometric Imaging Reveals Temporal and Spatial Dynamics of Bioactive Lipids in Arteries Undergoing Restenosis. Journal of Proteome Research. 2019;18:1669-1678.
Hu QF, Li Z, Wang LZ, Huang Y, Wang YT, Li LJ. Rainfall Spatial Estimations: A Review from Spatial Interpolation to Multi-Source Data Merging. Water. 2019;11.
DeLaney K, Li LJ. Data Independent Acquisition Mass Spectrometry Method for Improved Neuropeptidomic Coverage in Crustacean Neural Tissue Extracts. Analytical Chemistry. 2019;91:5150-5158.
Lajoie JM, Cho YK, Frost D, Bremner S, Li LJ, Shusta EV. A yeast display immunoprecipitation screen for targeted discovery of antibodies against membrane protein complexes. Protein Engineering Design & Selection. 2019;32:219-230.
Hao L, Thomas S, Greer T, Vezina CM, Bajpai S, Ashok A, et al. Quantitative proteomic analysis of a genetically induced prostate inflammation mouse model via custom 4-plex DiLeu isobaric labeling. American Journal of Physiology-Renal Physiology. 2019;316:F1236-F1243.
Acharya D, Miller I, Cui YS, Braun DR, Berres ME, Styles MJ, et al. Omics Technologies to Understand Activation of a Biosynthetic Gene Cluster in Micromonospora sp. WMMB235: Deciphering Keyicin Biosynthesis. ACS Chemical Biology. 2019;14:1260-1270.
Zhong XF, Frost DC, Li LJ. High-Resolution Enabled 5-plex Mass Defect-Based N,N-Dimethyl Leucine Tags for Quantitative Proteomics. Analytical Chemistry. 2019;91:7991-7995.
Liu Y, Buchberger AR, DeLaney K, Li ZH, Li LJ. Multifaceted Mass Spectrometric Investigation of Neuropeptide Changes in Atlantic Blue Crab, Callinectes sapidus, in Response to Low pH Stress. Journal of Proteome Research. 2019;18:2759-2770.
Ma FF, Tremmel DM, Li ZH, Lietz CB, Sackett SD, Odorico JS, et al. In Depth Quantification of Extracellular Matrix Proteins from Human Pancreas. Journal of Proteome Research. 2019;18:3156-3165.
Dieterich IA, Lawton AJ, Peng YJ, Yu Q, Rhoads TW, Overmyer KA, et al. Acetyl-CoA flux regulates the proteome and acetyl-proteome to maintain intracellular metabolic crosstalk. Nature Communications. 2019;10.
Vestal M, Li LJ, Dobrinskikh E, Shi YT, Wang BW, Shi XD, et al. Rapid MALDI-TOF molecular imaging: Instrument enhancements and their practical consequences. Journal of Mass Spectrometry. 2019;.
Hao L, Zhu YR, Wei PL, Johnson J, Buchberger A, Frost D, et al. Metandem: An online software tool for mass spectrometry-based isobaric labeling metabolomics. Analytica Chimica Acta. 2019;1088:99-106.
Li GY, Ma FF, Cao QJW, Zheng Z, DeLaney K, Liu R, et al. Nanosecond photochemically promoted click chemistry for enhanced neuropeptide visualization and rapid protein labeling. Nature Communications. 2019;10.
Liu R, Huang Y, Xu HK, Zheng YF, Liu Y, Han SY, et al. A strategy for identifying species-specific peptide biomarkers in deer-hide gelatin using untargeted and targeted mass spectrometry approaches. Analytica Chimica Acta. 2019;1092:32-41.
Shi YT, Li ZH, Felder MA, Yu QY, Shi XD, Peng YJ, et al. Mass Spectrometry Imaging of N-Glycans from Formalin-Fixed Paraffin-Embedded Tissue Sections Using a Novel Subatmospheric Pressure Ionization Source. Analytical Chemistry. 2019;91:12942-12947.
Li GY, DeLaney K, Li LJ. Molecular basis for chirality-regulated A beta self-assembly and receptor recognition revealed by ion mobility-mass spectrometry. Nature Communications. 2019;10.
Ruiz M, Yang Y, Lochbaum CA, Delafield DG, Pignatello JJ, Li LJ, et al. Peroxymonosulfate Oxidizes Amino Acids in Water without Activation. Environmental Science & Technology. 2019;53:10845-10854.
Chen BM, Zhong XF, Feng Y, Snovida S, Xu M, Rogers J, et al. Targeted MultiNotch MS3 Approach for Relative Quantification of N-Glycans Using Multiplexed Carbonyl-Reactive Isobaric Tags. Analytical Chemistry. 2018;90:1129-1135.
Chen BM, Lietz CB, Li LJ. Coupling matrix-assisted ionization with high resolution mass spectrometry and electron transfer dissociation to characterize intact proteins and post-translational modifications. Analytical and Bioanalytical Chemistry. 2018;410:1007-1017.
DeLaney K, Buchberger AR, Atkinson L, Grunder S, Mousley A, Li LJ. New techniques, applications and perspectives in neuropeptide research. Journal of Experimental Biology. 2018;221.
Buchberger AR, DeLaney K, Johnson J, Li LJ. Mass Spectrometry Imaging: A Review of Emerging Advancements and Future Insights. Analytical Chemistry. 2018;90:240-265.
Zhang YZ, DeLaney K, Hui LM, Wang JH, Sturm RM, Li LJ. A Multifaceted Mass Spectrometric Method to Probe Feeding Related Neuropeptide Changes in Callinectes sapidus and Carcinus maenas. Journal of the American Society for Mass Spectrometry. 2018;29:948-960.
Chen BM, Ouyang CZ, Tian ZC, Xu M, Li LJ. A high resolution atmospheric pressure matrix-assisted laser desorption/ionization-quadrupole-orbitrap MS platform enables in situ analysis of biomolecules by multi-mode ionization and acquisition. Analytica Chimica Acta. 2018;1007:16-25.
Stallcop LE, Alvarez-Garcia YR, Reyes-Ramos AM, Ramos-Cruz KP, Morgan MM, Shi YT, et al. Razor-printed sticker microdevices for cell-based applications. Lab on a Chip. 2018;18:451-462.
Chen ZW, Glover MS, Li LJ. Recent advances in ion mobility-mass spectrometry for improved structural characterization of glycans and glycoconjugates. Current Opinion in Chemical Biology. 2018;42:1-8.
Yao M, Chen BM, Zhao WP, Mehl JT, Li LJ, Zhu MS. LC-MS Differential Analysis for Fast and Sensitive Determination of Biotransformation of Therapeutic Proteins. Drug Metabolism and Disposition. 2018;46:451-457.
Yang N, Anapindi KDB, Rubakhin SS, Wei PL, Yu Q, Li LJ, et al. Neuropeptidomics of the Rat Habenular Nuclei. Journal of Proteome Research. 2018;17:1463-1473.
Glover MS, Yu Q, Chen ZW, Shi XD, Kent KC, Li LJ. Characterization of intact sialylated glycopeptides and phosphorylated glycopeptides from IMAC enriched samples by EThcD fragmentation: Toward combining phosphoproteomics and glycoproteomics. International Journal of Mass Spectrometry. 2018;427:35-42.
Ma FF, Sun RX, Tremmel DM, Sacket SD, Odorico J, Li LJ. Large-Scale Differentiation and Site Specific Discrimination of Hydroxyproline Isomers by Electron Transfer/Higher-Energy Collision Dissociation (EThcD) Mass Spectrometry. Analytical Chemistry. 2018;90:5857-5864.
Li LJ, Andren PE, Sweedler JV. Editorial and Review: 29th ASMS Sanibel Conference on Mass Spectrometry-Peptidomics: Bridging the Gap between Proteomics and Metabolomics by MS. Journal of the American Society for Mass Spectrometry. 2018;29:801-806.
Chen ZW, Yu Q, Hao L, Liu FB, Johnson J, Tian ZC, et al. Site-specific characterization and quantitation of N-glycopeptides in PKM2 knockout breast cancer cells using DiLeu isobaric tags enabled by electron-transfer/higher-energy collision dissociation (EThcD). Analyst. 2018;143:2508-2519.
Han SL, Lv YN, Kong LY, Sun YM, Fu J, Li LJ, et al. Simultaneous identification of the anaphylactoid components from traditional Chinese medicine injections using rat basophilic leukemia 2H3 and laboratory of allergic disease 2 dual-mixed/cell membrane chromatography model. Electrophoresis. 2018;39:1181-1189.
Cao QJW, Ouyang CZ, Zhong XF, Li LJ. Profiling of small molecule metabolites and neurotransmitters in crustacean hemolymph and neuronal tissues using reversed-phase LC-MS/MS. Electrophoresis. 2018;39:1241-1248.
Turski CA, Turski GN, Chen BM, Wang HH, Heidari M, Li LJ, et al. Clemastine effects in rat models of a myelination disorder. Pediatric Research. 2018;83:1200-1206.
Hao L, Wang JX, Page D, Asthana S, Zetterberg H, Carlsson C, et al. Comparative Evaluation of MS-based Metabolomics Software and Its Application to Preclinical Alzheimer's Disease. Scientific Reports. 2018;8.
Shearer MJ, Li MY, Li LJ, Jin S, Hamers RJ. Nanoscale Surface Photovoltage Mapping of 2D Materials and Heterostructures by Illuminated Kelvin Probe Force Microscopy. Journal of Physical Chemistry C. 2018;122:13564-13571.
Chen BM, Feng Y, Frost DC, Zhong XF, Buchberger AR, Johnson J, et al. Quantitative Glycomic Analysis by Mass-Defect-Based Dimethyl Pyrimidinyl Ornithine (DiPyrO) Tags and High -Resolution Mass. Analytical Chemistry. 2018;90:7817-7823.
Sackett SD, Tremmel DM, Ma FF, Feeney AK, Maguire RM, Brown ME, et al. Extracellular matrix scaffold and hydrogel derived from decellularized and delipidized human pancreas. Scientific Reports. 2018;8.
Ma FF, Liu FB, Xu W, Li LJ. Surfactant and Chaotropic Agent Assisted Sequential Extraction/On-Pellet Digestion (SCAD) for Enhanced Proteomics. Journal of Proteome Research. 2018;17:2744-2754.
Keller C, Maeda J, Jayaraman D, Chakraborty S, Sussman MR, Harris JM, et al. Comparison of Vacuum MALDI and AP-MALDI Platforms for the Mass Spectrometry Imaging of Metabolites Involved in Salt Stress in Medicago truncatula. Frontiers in Plant Science. 2018;9.
Jiang XY, Xiang F, Jia CX, Buchberger AR, Li LJ. Relative Quantitation of Neuropeptides at Multiple Developmental Stages of the American Lobster Using N,N-Dimethyl Leucine Isobaric Tandem Mass Tags. ACS Chemical Neuroscience. 2018;9:2054-2063.
Frost DC, Rust CJ, Robinson RAS, Li LJ. Increased N,N-Dimethyl Leucine Isobaric Tag Multiplexing by a Combined Precursor Isotopic Labeling and Isobaric Tagging Approach. Analytical Chemistry. 2018;90:10664-10669.
Sibilska I, Feng Y, Li LJ, Yin J. Trimetaphosphate Activates Prebiotic Peptide Synthesis across a Wide Range of Temperature and pH. Origins of Life and Evolution of Biospheres. 2018;48:277-287.
Hao L, Shi YT, Thomas S, Vezina CM, Bajpai S, Ashok A, et al. Comprehensive urinary metabolomic characterization of a genetically induced mouse model of prostatic inflammation. International Journal of Mass Spectrometry. 2018;434:185-192.
Bratburd JR, Keller C, Vivas E, Gemperline E, Li LJ, Rey FE, et al. Gut Microbial and Metabolic Responses to Salmonella enterica Serovar Typhimurium and Candida albicans. Mbio. 2018;9.
Hu CW, Worth M, Fan DC, Li BB, Li H, Lu L, et al. Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase. Nature Chemical Biology. 2017;13:1267-+.
Pang XQ, Jia CX, Chen ZW, Li LJ. Structural Characterization of Monomers and Oligomers of D-Amino Acid-Containing Peptides Using T-Wave Ion Mobility Mass Spectrometry. Journal of the American Society for Mass Spectrometry. 2017;28:110-118.
Hao L, Johnson J, Lietz CB, Buchberger A, Frost D, Kao WJ, et al. Mass Defect-Based N,N-Dimethyl Leucine Labels for Quantitative Proteomics and Amine Metabolomics of Pancreatic Cancer Cells. Analytical Chemistry. 2017;89:1138-1146.
Zhu YC, Takayama T, Wang BW, Kent A, Zhang MX, Binder BYK, et al. Restenosis Inhibition and Re-differentiation of TGF beta/Smad3-activated Smooth Muscle Cells by Resveratrol. Scientific Reports. 2017;7.
Yu Q, Shi XD, Feng Y, Kent KC, Li LJ. Improving data quality and preserving HCD-generated reporter ions with EThcD for isobaric tag-based quantitative proteomics and proteome-wide PTM studies. Analytica Chimica Acta. 2017;968:40-49.
Zhang XM, Jiang S, Mitok KA, Li LJ, Attie AD, Martin TFJ. BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells. Journal of Cell Biology. 2017;216:2151-2166.
Yu Q, Wang B, Chen Z, Urabe G, Glover MS, Shi X, et al. Electron-Transfer/Higher-Energy Collision Dissociation (EThcD)-Enabled Intact Glycopeptide/Glycoproteome Characterization. Journal of the American Society for Mass Spectrometry. 2017;:Ahead of Print.
Chen Z, Zhong X, Tie C, Chen B, Zhang X, Li LJ. Development of a hydrophilic interaction liquid chromatography coupled with matrix-assisted laser desorption/ionization-mass spectrometric imaging platform for N-glycan relative quantitation using stable-isotope labeled hydrazide reagents. Analytical and Bioanalytical Chemistry. 2017;409:4437-4447.
Gemperline E, Horn HA, DeLaney K, Currie CR, Li LJ. Imaging with Mass Spectrometry of Bacteria on the Exoskeleton of Fungus-Growing Ants. ACS Chemical Biology. 2017;12:1980-1985.
Yu Q, Canales A, Glover MS, Das R, Shi XD, Liu Y, et al. Targeted Mass Spectrometry Approach Enabled Discovery of O-Glycosylated Insulin and Related Signaling Peptides in Mouse and Human Pancreatic Islets. Analytical Chemistry. 2017;89:9184-9191.
Chen RB, Liu Y, Zhuang H, Yang BC, Hei KW, Xiao MM, et al. Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation. Nucleic Acids Research. 2017;45:9947-9959.
Ye H, Wang JX, Tian ZC, Ma FF, Dowell J, Bremer Q, et al. Quantitative Mass Spectrometry Reveals Food Intake-Induced Neuropeptide Level Changes in Rat Brain: Functional Assessment of Selected Neuropeptides as Feeding Regulators. Molecular & Cellular Proteomics. 2017;16:1922-1937.
Cheloha RW, Chen BM, Kumar NN, Watanabe T, Thorne RG, Li LJ, et al. Development of Potent, Protease-Resistant Agonists of the Parathyroid Hormone Receptor with Broad beta Residue Distribution. Journal of Medicinal Chemistry. 2017;60:8816-8833.
Fouque KJD, Garabedian A, Porter J, Baird M, Pang XQ, Williams TD, et al. Fast and Effective Ion Mobility-Mass Spectrometry Separation of D-Amino-Acid-Containing Peptides. Analytical Chemistry. 2017;89:11787-11794.
Ma M, Zhao XY, Chen S, Zhao YY, Yang L, Feng Y, et al. Strategy Based on Deglycosylation, Multiprotease, and Hydrophilic Interaction Chromatography for Large-Scale Profiling of Protein Methylation. Analytical Chemistry. 2017;89:12909-12917.
Adnani N, Chevrette MG, Adibhatla SN, Zhang F, Yu Q, Braun DR, et al. Coculture of Marine Invertebrate-Associated Bacteria and Interdisciplinary Technologies Enable Biosynthesis and Discovery of a New Antibiotic, Keyicin. ACS Chemical Biology. 2017;12:3093-3102.
Frost DC, Buchberger AR, Li LJ. Mass Defect-Based Dimethyl Pyrimidinyl Ornithine (DiPyrO) Tags for Multiplex Quantitative Proteomics. Analytical Chemistry. 2017;89:10798-10805.
Liu FB, Ma FF, Wang YY, Hao L, Zeng H, Jia CX, et al. PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis. Nature Cell Biology. 2017;19:1358-1370.
Lu JF, Zhong XF, Liu HS, Hao L, Huang CTL, Sherafat MA, et al. Generation of serotonin neurons from human pluripotent stem cells. Nature Biotechnology. 2016;34:89-94.
Keil KP, Abler LL, Altmann HM, Bushman W, Marker PC, Li LJ, et al. Influence of animal husbandry practices on void spot assay outcomes in C57BL/6J male mice. Neurourology and Urodynamics. 2016;35:192-198.
Chen BM, Lietz CB, Ouyang CZ, Zhong XF, Xu M, Li LJ. Matrix-assisted ionization vacuum for protein detection, fragmentation and PTM analysis on a high resolution linear ion trap-orbitrap platform. Analytica Chimica Acta. 2016;916:52-59.
Gemperline E, Keller C, Li LJ. Mass Spectrometry in Plant-omics. Analytical Chemistry. 2016;88:3422-3434.
Thomas S, Hao L, Ricke WA, Li LJ. Biomarker discovery in mass spectrometry-based urinary proteomics. Proteomics Clinical Applications. 2016;10:358-370.
Zhong XF, Hao L, Lu JF, Ye H, Zhang SC, Li LJ. Quantitative analysis of serotonin secreted by human embryonic stem cells-derived serotonergic neurons via pH-mediated online stacking-CE-ESI-MRM. Electrophoresis. 2016;37:1027-1030.
Jiang S, Liang ZD, Hao L, Li LJ. Investigation of signaling molecules and metabolites found in crustacean hemolymph via in vivo microdialysis using a multifaceted mass spectrometric platform. Electrophoresis. 2016;37:1031-1038.
Chesney AR, Booth CJ, Lietz CB, Li LJ, Pedersen JA. Peroxymonosulfate Rapidly Inactivates the Disease-Associated Prion Protein. Environmental Science & Technology. 2016;50:7095-7105.
Hullinger R, Li M, Wang JX, Peng YJ, Dowell JA, Bomba-Warczak E, et al. Increased expression of AT-1/SLC33A1 causes an autistic-like phenotype in mice by affecting dendritic branching and spine formation. Journal of Experimental Medicine. 2016;213:1267-1284.
Hao L, Greer T, Page D, Shi YT, Vezina CM, Macoska JA, et al. In-Depth Characterization and Validation of Human Urine Metabolomes Reveal Novel Metabolic Signatures of Lower Urinary Tract Symptoms. Scientific Reports. 2016;6.
Wang JX, Cunningham R, Zetterberg H, Asthana S, Carlsson C, Okonkwo O, et al. Label-free quantitative comparison of cerebrospinal fluid glycoproteins and endogenous peptides in subjects with Alzheimer's disease, mild cognitive impairment, and healthy individuals. Proteomics Clinical Applications. 2016;10:1225-1241.
Gemperline E, Keller C, Jayaraman D, Maeda J, Sussman MR, Ane JM, et al. Examination of Endogenous Peptides in Medicago truncatula Using Mass Spectrometry Imaging. Journal of Proteome Research. 2016;15:4403-4411.
Yu Q, Shi X, Greer T, Lietz CB, K. Kent C, Li LJ. Evaluation and Application of Dimethylated Amino Acids as Isobaric Tags for Quantitative Proteomics of the TGF-β/Smad3 Signaling Pathway. Journal of Proteome Research. 2016;15:3420-3431.
Jia C, Lietz CB, Yu Q, Li LJ. Site-specific Localization of D-Amino Acids in Bioactive Peptides by Ion Mobility Spectrometry. Neuromethods. 2016;114:43-53.
Lietz CB, Chen Z, Son CYun, Pang X, Cui Q, Li LJ. Multiple gas-phase conformations of proline-containing peptides: is it always cis/trans isomerization?. Analyst. 2016;141:4863-4869.
Zhong XF, Chen ZW, Snovida S, Liu Y, Rogers JC, Li LJ. Capillary Electrophoresis-Electrospray Ionization-Mass Spectrometry for Quantitative Analysis of Glycans Labeled with Multiplex Carbonyl-Reactive Tandem Mass Tags. Analytical Chemistry. 2015;87:6527-6534.
Hao L, Zhong XF, Greer T, Ye H, Li LJ. Relative quantification of amine-containing metabolites using isobaric N,N-dimethyl leucine (DiLeu) reagents via LC-ESI-MS/MS and CE-ESI-MS/MS. Analyst. 2015;140:467-475.
Greer T, Lietz CB, Xiang F, Li LJ. Novel isotopic N,N-Dimethyl Leucine (iDiLeu) Reagents Enable Absolute Quantification of Peptides and Proteins Using a Standard Curve Approach. Journal of the American Society for Mass Spectrometry. 2015;26:107-119.
Gemperline E, Jayaraman D, Maeda J, Ane JM, Li LJ. Multifaceted Investigation of Metabolites During Nitrogen Fixation in Medicago via High Resolution MALDI-MS Imaging and ESI-MS. Journal of the American Society for Mass Spectrometry. 2015;26:149-158.
Schmerberg CM, Liang ZD, Li LJ. Data-Independent MS/MS Quantification of Neuropeptides for Determination of Putative Feeding-Related Neurohormones in Microdialysate. ACS Chemical Neuroscience. 2015;6:174-180.
Frost DC, Greer T, Li LJ. High-Resolution Enabled 12-Plex DiLeu Isobaric Tags for Quantitative Proteomics. Analytical Chemistry. 2015;87:1646-1654.
Frost DC, Greer T, Xiang F, Liang ZD, Li LJ. Development and characterization of novel 8-plex DiLeu isobaric labels for quantitative proteomics and peptidomics. Rapid Communications in Mass Spectrometry. 2015;29:1115-1124.
Liang ZD, Schmerberg CM, Li LJ. Mass spectrometric measurement of neuropeptide secretion in the crab, Cancer borealis, by in vivo microdialysis. Analyst. 2015;140:3803-3813.
Gushue D, Herbst A, Li LJ, McKenzie D, Aiken J. Pre-clinical biomarkers of prion infection. Prion. 2015;9:S51-S52.
Ouyang CZ, Liang ZD, Li LJ. Mass spectrometric analysis of spatio-temporal dynamics of crustacean neuropeptides. Biochimica Et Biophysica Acta-Proteins and Proteomics. 2015;1854:798-811.
Greer T, Hao L, Nechyporenko A, Lee S, Vezina CM, Ricke WA, et al. Custom 4-Plex DiLeu Isobaric Labels Enable Relative Quantification of Urinary Proteins in Men with Lower Urinary Tract Symptoms (LUTS). Plos One. 2015;10.
Jiang S, Zhang ZC, Li LJ. A one-step preparation method of monolithic enzyme reactor for highly efficient sample preparation coupled to mass spectrometry-based proteomics studies. Journal of Chromatography A. 2015;1412:75-81.
Ye H, Wang JX, Zhang ZC, Jia CX, Schmerberg C, Catherman AD, et al. Defining the Neuropeptidome of the Spiny Lobster Panulirus interruptus Brain Using a Multidimensional Mass Spectrometry-Based Platform. Journal of Proteome Research. 2015;14:4776-4791.
Ouyang CZ, Chen BM, Li LJ. High Throughput In Situ DDA Analysis of Neuropeptides by Coupling Novel Multiplex Mass Spectrometric Imaging (MSI) with Gas-Phase Fractionation. Journal of the American Society for Mass Spectrometry. 2015;26:1992-2001.
Zhang YZ, Buchberger A, Muthuvel G, Li LJ. Expression and distribution of neuropeptides in the nervous system of the crab Carcinus maenas and their roles in environmental stress. Proteomics. 2015;15:3969-3979.
Cohen HCaitlin, Frost DC, Lieberthal TJacob, Li LJ, W. Kao J. Biomaterials differentially regulate Src kinases and phosphoinositide 3-kinase-γ in polymorphonuclear leukocyte primary and tertiary granule release. Biomaterials. 2015;50:47-55.
Buchberger A, Yu Q, Li LJ. Advances in Mass Spectrometric Tools for Probing Neuropeptides. Annual Review of Analytical Chemistry. 2015;8:485-509.
Frost DC, Li LJ. Recent Advances in Mass Spectrometry-Based Glycoproteomics. In: Donev R. 2014. pp. 71-123.
Gemperline E, Li LJ. MALDI-Mass Spectrometric Imaging for the Investigation of Metabolites in Medicago truncatula Root Nodules. Jove-Journal of Visualized Experiments. 2014;.
Jia CX, Lietz CB, Yu Q, Li LJ. Site-Specific Characterization of D-Amino Acid Containing Peptide Epimers by Ion Mobility Spectrometry. Analytical Chemistry. 2014;86:2972-2981.
Sturm RM, Lietz CB, Li LJ. Improved isobaric tandem mass tag quantification by ion mobility mass spectrometry. Rapid Communications in Mass Spectrometry. 2014;28:1051-1060.
Ye H, Mandal R, Catherman A, Thomas PM, Kelleher NL, Ikonomidou C, et al. Top-Down Proteomics with Mass Spectrometry Imaging: A Pilot Study towards Discovery of Biomarkers for Neurodevelopmental Disorders. Plos One. 2014;9.
Zhong XF, Zhang ZC, Jiang S, Li LJ. Recent advances in coupling capillary electrophoresis- based separation techniques to ESI and MALDI-MS. Electrophoresis. 2014;35:1214-1225.
Gushue DL, Herbst A, Li LJ, McKenzie D, Aiken J. Identification of ante-mortem prion disease biomarkers. Prion. 2014;8:78-78.
Gemperline E, Laha K, Scarlett CO, Pearce RA, Li LJ. Measurement of NMDA receptor antagonist, CPP, in mouse plasma and brain tissue following systemic administration using ion-pair LC-MS/MS. Analytical Methods. 2014;6:6389-6396.
Katsumura KR, Yang CX, Boyer ME, Li LJ, Bresnick EH. Molecular basis of crosstalk between oncogenic Ras and the master regulator of hematopoiesis GATA-2. Embo Reports. 2014;15:938-947.
Gemperline E, Rawson S, Li LJ. Optimization and Comparison of Multiple MALDI Matrix Application Methods for Small Molecule Mass Spectrometric Imaging. Analytical Chemistry. 2014;86:10030-10035.
Lietz CB, Yu Q, Li LJ. Large-Scale Collision Cross-Section Profiling on a Traveling Wave Ion Mobility Mass Spectrometer. Journal of the American Society for Mass Spectrometry. 2014;25:2009-2019.
Yang CX, Zhong XF, Li LJ. Recent advances in enrichment and separation strategies for mass spectrometry-based phosphoproteomics. Electrophoresis. 2014;35:3418-3429.
Chen RB, Xiao MM, Buchberger A, Li LJ. Quantitative Neuropeptidomics Study of the Effects of Temperature Change in the Crab Cancer borealis. Journal of Proteome Research. 2014;13:5767-5776.
Gemperline E, Chen BM, Li LJ. Challenges and recent advances in mass spectrometric imaging of neurotransmitters. Bioanalysis. 2014;6:525-540.
Jia CX, Wu Z, Lietz CB, Liang ZD, Cui Q, Li LJ. Gas-Phase Ion Isomer Analysis Reveals the Mechanism of Peptide Sequence Scrambling. Analytical Chemistry. 2014;86:2917-2924.
Jia CX, Yu Q, Wang JX, Li LJ. Qualitative and quantitative top-down mass spectral analysis of crustacean hyperglycemic hormones in response to feeding. Proteomics. 2014;14:1185-1194.
Chen RB, Ouyang CZ, Xiao MM, Li LJ. In situ identification and mapping of neuropeptides from the stomatogastric nervous system of Cancer borealis. Rapid Communications in Mass Spectrometry. 2014;28:2437-2444.
Chen BM, Lietz CB, Li LJ. In Situ Characterization of Proteins Using Laserspray Ionization on a High-Performance MALDI-LTQ-Orbitrap Mass Spectrometer. Journal of the American Society for Mass Spectrometry. 2014;25:2177-2180.
Lietz CB, Gemperline E, Li LJ. Qualitative and quantitative mass spectrometry imaging of drugs and metabolites. Advanced Drug Delivery Reviews. 2013;65:1074-1085.
Ma D, Cao WF, Kapur A, Felder M, Scarlett CO, Patankar MS, et al. Differential expression of proteins in naive and IL-2 stimulated primary human NK cells identified by global proteomic analysis. Journal of Proteomics. 2013;91:151-163.
Rodgers EW, Krenz WD, Jiang XY, Li LJ, Baro DJ. Dopaminergic tone regulates transient potassium current maximal conductance through a translational mechanism requiring D1Rs, cAMP/PKA, Erk and mTOR
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Schmerberg CM, Li LJ. Function-Driven Discovery of Neuropeptides with Mass Spectrometry-Based Tools. Protein and Peptide Letters. 2013;20:681-694.
Schmerberg CM, Li LJ. Mass Spectrometric Detection of Neuropeptides Using Affinity-Enhanced Microdialysis with Antibody-Coated Magnetic Nanoparticles. Analytical Chemistry. 2013;85:915-922.
Sturm RM, Greer T, Chen RB, Hensen B, Li LJ. Comparison of NIMS and MALDI platforms for neuropeptide and lipid mass spectrometric imaging in C. borealis brain tissue. Analytical Methods. 2013;5:1623-1628.
Sturm RM, Greer T, Woodards N, Gemperline E, Li LJ. Mass Spectrometric Evaluation of Neuropeptidomic Profiles upon Heat Stabilization Treatment of Neuroendocrine Tissues in Crustaceans. Journal of Proteome Research. 2013;12:743-752.
Ye H, Gemperline E, Li LJ. A vision for better health: Mass spectrometry imaging for clinical diagnostics. Clinica Chimica Acta. 2013;420:11-22.
Ye H, Gemperline E, Venkateshwaran M, Chen RB, Delaux PM, Howes-Podoll M, et al. MALDI mass spectrometry-assisted molecular imaging of metabolites during nitrogen fixation in the Medicago truncatula-Sinorhizobium meliloti symbiosis. Plant Journal. 2013;75:130-145.
Ye H, Hui LM, Kellersberger K, Li LJ. Mapping of Neuropeptides in the Crustacean Stomatogastric Nervous System by Imaging Mass Spectrometry. Journal of the American Society for Mass Spectrometry. 2013;24:134-147.
Ye H, Wang JX, Greer T, Strupat K, Li LJ. Visualizing Neurotransmitters and Metabolites in the Central Nervous System by High Resolution and High Accuracy Mass Spectrometric Imaging. ACS Chemical Neuroscience. 2013;4:1049-1056.
Zhang J, Lanham KA, Heideman W, Peterson RE, Li LJ. Statistically Enhanced Spectral Counting Approach to TCDD Cardiac Toxicity in the Adult Zebrafish Heart. Journal of Proteome Research. 2013;12:3093-3103.
Zhang ZC, Jiang S, Li LJ. Semi-automated liquid chromatography-mass spectrometric imaging platform for enhanced detection and improved data analysis of complex peptides. Journal of Chromatography A. 2013;1293:44-50.
Zhang ZC, Kuang J, Li LJ. Liquid chromatography-matrix-assisted laser desorption/ionization mass spectrometric imaging with sprayed matrix for improved sensitivity, reproducibility and quantitation. Analyst. 2013;138:6600-6606.
Cunningham R, Jany P, Messing A, Li LJ. Protein Changes in Immunodepleted Cerebrospinal Fluid from a Transgenic Mouse Model of Alexander Disease Detected Using Mass Spectrometry. Journal of Proteome Research. 2013;12:719-728.
Hui LM, D'Andrea BT, Jia CX, Liang ZD, Christie AE, Li LJ. Mass spectrometric characterization of the neuropeptidome of the ghost crab Ocypode ceratophthalma (Brachyura, Ocypodidae). General and Comparative Endocrinology. 2013;184:22-34.
Jia CX, Lietz CB, Ye H, Hui LM, Yu Q, Yoo S, et al. A multi-scale strategy for discovery of novel endogenous neuropeptides in the crustacean nervous system. Journal of Proteomics. 2013;91:1-12.
Cunningham R, Wang JX, Wellner D, Li LJ. Investigation and reduction of sub-microgram peptide loss using molecular weight cut-off fractionation prior to mass spectrometric analysis. Journal of Mass Spectrometry. 2012;47:1327-1332.
Hui LM, Xiang F, Zhang YZ, Li LJ. Mass spectrometric elucidation of the neuropeptidome of a crustacean neuroendocrine organ. Peptides. 2012;36:230-239.
Jia CX, Hui LM, Cao WF, Lietz CB, Jiang XY, Chen RB, et al. High-definition De Novo Sequencing of Crustacean Hyperglycemic Hormone (CHH)-family Neuropeptides. Molecular & Cellular Proteomics. 2012;11:1951-1964.
Jiang XY, Chen RB, Wang JH, Metzler A, Tlusty M, Li LJ. Mass Spectral Charting of Neuropeptidomic Expression in the Stomatogastric Ganglion at Multiple Developmental Stages of the Lobster Homarus americanus. ACS Chemical Neuroscience. 2012;3:439-450.
Ma D, Li LJ. Searching for reliable premortem protein biomarkers for prion diseases: progress and challenges to date. Expert Review of Proteomics. 2012;9:267-280.
Zhang ZC, Jia CX, Li LJ. Neuropeptide analysis with liquid chromatography-capillary electrophoresis-mass spectrometric imaging. Journal of Separation Science. 2012;35:1779-1784.
Zhang ZC, Wang JH, Hui LM, Li LJ. Poly(glycidyl methacrylate-divinylbenzene) based immobilized pH gradient capillary isoelectric focusing coupling with MALDI mass spectrometry for enhanced neuropeptide analysis. Electrophoresis. 2012;33:661-665.
Sturm R, Sheynkman G, Booth C, Smith LM, Pedersen JA, Li LJ. Absolute Quantification of Prion Protein (90-231) Using Stable Isotope-Labeled Chymotryptic Peptide Standards in a LC-MRM AQUA Workflow. Journal of the American Society for Mass Spectrometry. 2012;23:1522-1533.
Ye H, Greer T, Li LJ. Probing neuropeptide signaling at the organ and cellular domains via imaging mass spectrometry. Journal of Proteomics. 2012;75:5014-5026.
Hui L, Cunningham R, Zhang Z, Cao W, Jia C, Li LJ. Discovery and Characterization of the Crustacean Hyperglycemic Hormone Precursor Related Peptides (CPRP) and Orcokinin Neuropeptides in the Sinus Glands of the Blue Crab Callinectes sapidus Using Multiple Tandem Mass Spectrometry Techniques. Journal of Proteome Research. 2011;10:4219-4229.
Szabo TM, Chen R, Goeritz ML, Maloney RT, Tang LS, Li LJ, et al. Distribution and Physiological Effects of B-Type Allatostatins (Myoinhibitory Peptides, MIPs) in the Stomatogastric Nervous System of the Crab Cancer borealis. Journal of Comparative Neurology. 2011;519:2658-2676.
Wang J, Ye H, Zhang Z, Xiang F, Girdaukas G, Li LJ. Advancing Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometric Imaging for Capillary Electrophoresis Analysis of Peptides. Analytical Chemistry. 2011;83:3462-3469.
Wei X, Herbst A, Ma D, Aiken J, Li LJ. A Quantitative Proteomic Approach to Prion Disease Biomarker Research: Delving into the Glycoproteome. Journal of Proteome Research. 2011;10:2687-2702.
Ye H, Greer T, Li LJ. From pixel to voxel: a deeper view of biological tissue by 3D mass spectral imaging. Bioanalysis. 2011;3:313-332.
Zhang Z, Wang J, Hui L, Li LJ. Membrane-assisted capillary isoelectric focusing coupling with matrix-assisted laser desorption/ionization-Fourier transform mass spectrometry for neuropeptide analysis. Journal of Chromatography A. 2011;1218:5336-5343.
Chen R, Hui L, Cape SS, Wang J, Li LJ. Comparative Neuropeptidomic Analysis of Food Intake via a Multifaceted Mass Spectrometric Approach. ACS Chemical Neuroscience. 2010;1:204-214.
Chen R, Jiang X, Conaway MCPrieto, Mohtashemi I, Hui L, Viner R, et al. Mass Spectral Analysis of Neuropeptide Expression and Distribution in the Nervous System of the Lobster Homarus americanus. Journal of Proteome Research. 2010;9:818-832.
Chen R, Li LJ. Mass spectral imaging and profiling of neuropeptides at the organ and cellular domains. Analytical and Bioanalytical Chemistry. 2010;397:3185-3193.
Herbst A, Wei X, Ma D, Li LJ, Aiken J. Quantitative Proteomic Analysis of Prion Infected Mouse Plasma. Prion. 2010;4:218-218.
Ma M, Gard AL, Xiang F, Wang J, Davoodian N, Lenz PH, et al. Combining in silico transcriptome mining and biological mass spectrometry for neuropeptide discovery in the Pacific white shrimp Litopenaeus vannamei. Peptides. 2010;31:27-43.
Wang J, Zhang Y, Xiang F, Zhang Z, Li LJ. Combining capillary electrophoresis matrix-assisted laser desorption/ionization mass spectrometry and stable isotopic labeling techniques for comparative crustacean peptidomics. Journal of Chromatography A. 2010;1217:4463-4470.
Wei X, Dulberger C, Li LJ. Characterization of Murine Brain Membrane Glycoproteins by Detergent Assisted Lectin Affinity Chromatography. Analytical Chemistry. 2010;82:6329-6333.
Xiang F, Ye H, Chen R, Fu Q, Li LJ. N,N-Dimethyl Leucines as Novel Isobaric Tandem Mass Tags for Quantitative Proteomics and Peptidomics. Analytical Chemistry. 2010;82:2817-2825.
Zhang J, Lanham KA, Peterson RE, Heideman W, Li LJ. Characterization of the adult zebrafish cardiac proteome using online pH gradient strong cation exchange-RP 2D LC coupled with ESI MS/MS. Journal of Separation Science. 2010;33:1462-1471.
Chen RB, Hui LM, Sturm RM, Li LJ. Three Dimensional Mapping of Neuropeptides and Lipids in Crustacean Brain by Mass Spectral Imaging. Journal of the American Society for Mass Spectrometry. 2009;20:1068-1077.
Cho YK, Chen I, Wei X, Li LJ, Shusta EV. A yeast display immunoprecipitation method for efficient isolation and characterization of antigens. Journal of Immunological Methods. 2009;341:117-126.
Dowell JA, Johnson JA, Li LJ. Identification of Astrocyte Secreted Proteins with a Combination of Shotgun Proteomics and Bioinformatics. Journal of Proteome Research. 2009;8:4135-4143.
Ma M, Sturm RM, Kutz-Naber KK, Fu Q, Li LJ. Immunoaffinity-based mass spectrometric characterization of the FMRFamide-related peptide family in the pericardial organ of Cancer borealis. Biochemical and Biophysical Research Communications. 2009;390:325-330.
Ma MM, Bors EK, Dickinson ES, Kwiatkowski MA, Sousa GL, Henry RP, et al. Characterization of the Carcinus maenas neuropeptidome by mass spectrometry and functional genomics. General and Comparative Endocrinology. 2009;161:320-334.
Ma MM, Chen RB, Ge Y, He H, Marshall AG, Li LJ. Combining Bottom-Up and Top-Down Mass Spectrometric Strategies for De Novo Sequencing of the Crustacean Hyperglycemic Hormone from Cancer borealis. Analytical Chemistry. 2009;81:240-247.
Ma MM, Szabo TM, Jia CX, Marder E, Li LJ. Mass spectrometric characterization and physiological actions of novel crustacean C-type allatostatins. Peptides. 2009;30:1660-1668.
Thomas-Virnig CL, Centanni JM, Johnston CE, He LK, Schlosser SJ, Van Winkle KF, et al. Inhibition of Multidrug-resistant Acinetobacter baumannii by Nonviral Expression of hCAP-18 in a Bioengineered Human Skin Tissue. Molecular Therapy. 2009;17:562-569.
Ma M, Chen R, Sousa GL, Bors EK, Kwiatkowski MA, Goiney CC, et al. Mass spectral characterization of peptide transmitters/hormones in the nervous system and neuroendocrine organs of the American lobster Homarus americanus. General and Comparative Endocrinology. 2008;156:395-409.
Christie AE, Cashman CR, Brennan HR, Ma M, Sousa GL, Li LJ, et al. Identification of putative crustacean neuropeptides using in silico analyses of publicly accessible expressed sequence tags. General and Comparative Endocrinology. 2008;156:246-264.
Schmidt JJ, McLlwain S, Page D, Christie AE, Li LJ. Combining MALDI-FTMS and bioinformatics for rapid peptidomic comparisons. Journal of Proteome Research. 2008;7:887-896.
Saideman SR, Ma M, Kutz-Naber KK, Cook A, Torfs P, Schoofs L, et al. Modulation of rhythmic motor activity by pyrokinin peptides. Journal of Neurophysiology. 2007;97:579-595.
DeKeyser SS, Kutz-Naber KK, Schmidt JJ, Barrett-Wilt GA, Li LJ. Imaging mass spectrometry of neuropeptides in decapod crustacean neuronal tissues. Journal of Proteome Research. 2007;6:1782-1791.
Dickinson PS, Stevens JS, Rus S, Brennan HR, Goiney CC, Smith CM, et al. Identification and cardiotropic actions of sulfakinin peptides in the American lobster Homarus americanus. Journal of Experimental Biology. 2007;210:2278-2289.
Zhao L, Shi X, Li LJ, Miller DJ. Dynamin 2 associates with complexins and is found in the acrosomal region of mammalian sperm. Molecular Reproduction and Development. 2007;74:750-757.
Fu Q, Li LJ. Neutral loss of water from the b ions with histidine at the C-terminus and formation of the c ions involving lysine side chains. Journal of Mass Spectrometry. 2006;41:1600-1607.
Fu Q, Li LJ. Investigation of several unique tandem mass spectrometric fragmentation patterns of NFDEIDR, an orcokinin analog, and its N-terminal dimethylated form. Rapid Communications in Mass Spectrometry. 2006;20:553-562.
Messinger DI, Kutz KK, Le T, Verley DR, Hsu YWA, Ngo CT, et al. Identification and characterization of a tachykinin-containing neuroendocrine organ in the commissural ganglion of the crab Cancer productus. Journal of Experimental Biology. 2005;208:3303-3319.
Proekt A, Vilim FS, Alexeeva V, Brezina V, Friedman A, Jing J, et al. Identification of a new neuropeptide precursor reveals a novel source of extrinsic modulation in the feeding system of Aplysia. Journal of Neuroscience. 2005;25:9637-9648.
Yew JY, Kutz KK, Dikler S, Messinger L, Li LJ, Stretton AO. Mass spectrometric map of neuropeptide expression in Ascaris suum. Journal of Comparative Neurology. 2005;488:396-413.
Fu Q, Goy MF, Li LJ. Identification of neuropeptides from the decapod crustacean sinus glands using nanoscale liquid chromatography tandem mass spectrometry. Biochemical and Biophysical Research Communications. 2005;337:765-778.
Fu Q, Christie AE, Li LJ. Mass spectrometric characterization of crustacean hyperglycemic hormone precursor-related peptides (CPRPs) from the sinus gland of the crab, Cancer productus. Peptides. 2005;26:2137-2150.
Fu Q, Kutz KK, Schmidt JJ, Hsu YWA, Messinger DI, Cain SD, et al. Hormone complement of the Cancer productus sinus gland and pericardial organ: An anatomical and mass spectrometric investigation [Review]. Journal of Comparative Neurology. 2005;493:607-626.
Fu Q, Li LJ. De novo sequencing of neuropeptides using reductive isotopic methylation and investigation of ESI QTOF MS/MS fragmentation pattern of neuropeptides with N-terminal dimethylation. Analytical Chemistry. 2005;77:7783-7795.
Kutz KK, Schmidt JJ, Li LJ. In situ tissue analysis of neuropeptides by MALDI FTMS in-cell accumulation. Analytical Chemistry. 2004;76:5630-5640.
Hummon AB, Hummon NP, Corbin RW, Li LJ, Vilim FS, Weiss KR, et al. From precursor to final peptides: A statistical sequence-based approach to predicting prohormone processing. Journal of Proteome Research. 2003;2:650-656.
Li LJ, Kelley WP, Billimoria CP, Christie AE, Pulver SR, Sweedler JV, et al. Mass spectrometric investigation of the neuropeptide complement and release in the pericardial organs of the crab, Cancer borealis. Journal of Neurochemistry. 2003;87:642-656.
Masselon C, Pasa-Tolic L, Li LJ, Anderson GA, Harkewicz R, Smith RD. Identification of tryptic peptides from large databases using multiplexed tandem mass spectrometry: simulations and experimental results. Proteomics. 2003;3:1279-1286.
Li LJ, Sweedler JV. Measuring neuropeptides with single-cell MALDI-MS. In: Silberring J, Ekman R. Mass Spectrometry And Hyphenated Techniques In Neuropeptide Research. New York: Wiley and Sons, Inc.; 2002. pp. 495-517.
Li LJ, Pulver SR, Kelley WP, Thirumalai V, Sweedler JV, Marder E. Orcokinin peptides in developing and adult crustacean stomatogastric nervous systems and pericardial organs. Journal of Comparative Neurology. 2002;444:227-244.
Li LJ, Romanova EV, Rubakhin SS, Alexeeva V, Weiss KR, Vilim FS, et al. Peptide profiling of cells with multiple gene products: Combining immunochemistry and MALDI mass spectrometry with on-plate microextraction. Analytical Chemistry. 2000;72:3867-3874.
Li LJ, Garden RW, Sweedler JV. Single-cell MALDI: a new tool for direct peptide profiling. Trends in Biotechnology. 2000;18:151-160.
Sweedler JV, Li LJ, Floyd P, Gilly W. Mass spectrometric survey of peptides in cephalopods with an emphasis on the FMRFamide-related peptides. Journal of Experimental Biology. 2000;203:3565-3573.
Li LJ, Garden RW, Floyd PD, Moroz TP, Gleeson JM, Sweedler JV, et al. Egg-laying hormone peptides in the Aplysiidae family. Journal of Experimental Biology. 1999;202:2961-2973.
Li LJ, Garden RW, Romanova EV, Sweedler JV. In situ sequencing of peptides from biological tissues and single cells using MALDI-PSD/CID analysis. Analytical Chemistry. 1999;71:5451-5458.
Rubakhin SS, Li LJ, Moroz TP, Sweedler JV. Characterization of the Aplysia californica cerebral ganglion F cluster. Journal of Neurophysiology. 1999;81:1251-1260.
Garden RW, Moroz TP, Gleeson JM, Floyd PD, Li LJ, Rubakhin SS, et al. Formation of N-pyroglutamyl peptides from N-Glu and N-Gln precursors in Aplysia neurons. Journal of Neurochemistry. 1999;72:676-681.
Floyd PD, Li LJ, Rubakhin SS, Sweedler JV, Horn CC, Kupfermann I, et al. Insulin prohormone processing, distribution, and relation to metabolism in Aplysia californica. Journal of Neuroscience. 1999;19:7732-7741.
Floyd PD, Li LJ, Moroz TP, Sweedler JV. Characterization of peptides from Aplysia using microbore liquid chromatography with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry guided purification. Journal of Chromatography A. 1999;830:105-113.
Garden RW, Shippy SA, Li LJ, Moroz TP, Sweedler JV. Proteolytic processing of the Aplysia egg-laying hormone prohormone. Proceedings of the National Academy of Sciences of the United States of America. 1998;95:3972-3977.
Li LJ, Moroz TP, Garden RW, Floyd PD, Weiss KR, Sweedler JV. Mass spectrometric survey of interganglionically transported peptides in Aplysia. Peptides. 1998;19:1425-1433.
Jiang K, Li LJ, Chen Y, Jin J. Determination of PCDD/Fs and dioxin-like PCBs in Chinese commercial PCBs and emissions from a testing PCB incinerator. Chemosphere. 1997;34:941-950.
Schecter A, Li LJ. Dioxins, dibenzofurans, dioxin-like PCBs, and DDE in U.S. fast food, 1995. Chemosphere. 1997;34:1449-1457.
Schecter A, Paepke O, Lis A, Ball M, Rayan JJ, Olson JR, et al. Decrease in milk and blood dioxin levels over two years in a mother nursing twins: estimates of decreased maternal and increased infant dioxin body burden from nursing. Chemosphere. 1996;32:543-9.
Jiang K, Li LJ, Chen Y. Dioxins in stack ash from PCB waste incinerator. Huanjing Kexue. 1996;17:68-71.
Jiang K, Chen Y, Li LJ. PCDD/Fs in sodium pentachlorophenate (Na - PCP) and human blood, milk and sediment samples from Chinese schistosomiasis areas. J. Environ. Sci. (China). 1995;7:52-9.
Jiang K, Li LJ, Chen Y, Li S, Gong Y. Residual dioxins in Chinese schistosomiasis region and its eco-environmental risk. Chinese Science Bulletin. 1995;40:1740-7.
Jin J, Li LJ, Jiang K. Toxicity of dioxin-like compounds. Shanghai Huanjing Kexue. 1995;14:29-32, 42.
Li LJ, Chen Y, Zhou Y, Wu J, Jiang K. Use of acid-base silica/alumina column and gas chromatography-mass spectrometry (GC/MS) methods for determination of residual PCBs in the solid wastes of an incinerator. Huanjing Huaxue. 1995;14:322-8.
Li LJ, Jiang K. Determination of dioxin-like PCB (halocarbon) in both commercially available PCBs in China and stack ash from PCB incinerator. Huanjing Kexue. 1995;16:55-8.
Li LJ, Jiang K. Determination of toxic equivalents of PCDD/Fs in two Chinese commercial PCBs by 13C isotope dilution method. Huanjing Kexue Xuebao. 1995;15:433-9.
Schecter A, Li LJ, Olson JR. Dioxins in U.S. fast food. Organohalogen Compd. 1995;26:135-9.
Li LJ, Chen Y, Chiu C, Poole G, Miles W, Jiang K. PCDD/Fs in sediment samples from Chinese schistosomiasis areas and potential human health effects. Organohalogen Compd. 1994;20:155-8.
Li LJ, Wu J, Chen Y, Jiang K. Determination of polychlorinated biphenyls in transformer oils. Huanjing Kexue. 1993;14:69-72.