Protein 1

Table of Contents
Biomolecules Gateway Page
Jmol Tutorial

In this module:

Amino Acids
Hydrophobic and Polar Amino Acids
Acidic and Basic Amino Acids
Peptide Bonds
Planarity of Peptide Bonds
Protein Sequences
Sickle Cell Anemia

Protein Sequences (Primary Structure)

Many proteins have thousands of amino acids. To save space, their sequences are usually written using the abbreviated amino acid names, like the three-letter codes used in this module.

Does the order of the amino acids when written on paper make a difference in the structure? For example, is Ala-Ser the same as Ser-Ala? It turns out that they're not. For example, shown at the right is the structure of Ala-Ser. Notice how the Ala has a free amine group (the -NH3+ group) while the Ser has a free acid group (the -COO- group). By convention, protein sequences are written from the end with the free -NH3+ group (the N terminus ) to the end with the free -COO- group (the C terminus ).

Shown below is the structure formed by three amino acids linked by peptide bonds. Select its name from the following list using the three-letter codes. Click on the Protein 1 icon to see the structures of the amino acids.

Thr-Met-Gly Asn-Thr-Arg Arg-Thr-Asn Asp-Thr-Arg

You have picked incorrect amino acids.


You have picked the incorrect N- to C-terminal orientation.

You have chosen an incorrect name for the first amino acid.

Protein Sequences (Primary Structure)